American Chemical Society
Browse

Extending Pummerer Reaction Chemistry. Synthesis of (±)-Dibromophakellstatin by Oxidative Cyclization of an Imidazole Derivative

Download (3.05 MB)
journal contribution
posted on 2005-03-03, 00:00 authored by Ken S. Feldman, Amanda P. Skoumbourdis
The diastereoselective oxidative cyclization of a dihydrooroidin derivative is reported. The thioimidate product formed by application of a new variant of the Pummerer reaction serves as a precursor to dibromophakellstatin.

History