Exploring Tandem Ruthenium-Catalyzed Hydrogen Transfer and SNAr Chemistry
journal contribution
posted on 2017-12-06, 15:21 authored by Kurt Polidano, Benjamin G. Reed-Berendt, Anaïs Basset, Andrew J. A. Watson, Jonathan M. J. Williams, Louis C. MorrillA hydrogen-transfer strategy for
the catalytic functionalization
of benzylic alcohols via electronic arene activation, accessing a
diverse range of bespoke diaryl ethers and aryl amines in excellent
isolated yields (38 examples, 70% average yield), is reported. Taking
advantage of the hydrogen-transfer approach, the oxidation level of
the functionalized products can be selected by judicious choice of
simple and inexpensive additives.
