posted on 2021-10-05, 15:18authored bySiti Nurhanna Riduan, Guangshun Yi, Shujun Gao, Jeremy Pang Kern Tan, Yee Lin Tan, Yuan Yuan, Hongfang Lu, Shuyun Chng, Jin Ting Ong, Pei Yun Hon, Mohammad Yazid Abdad, Shawn Vasoo, Brenda SP Ang, Yi Yan Yang, Jackie Y. Ying, Yugen Zhang
Much
attention has been devoted to the synthesis and antimicrobial
studies of nanopatterned surfaces. However, factors contributing to
their potential and eventual application, such as large-scale synthesis,
material durability, and biocompatibility, are often neglected in
such studies. In this paper, the ZnO nanopillar surface is found to
be amenable to synthesis in large forms and stable upon exposure to
highly accelerated lifetime tests (HALT) without any detrimental effect
on its antimicrobial activity. Additionally, the material is effective
against clinically isolated pathogens and biocompatible in
vivo. These findings illustrate the broad applicability of
ZnO nanopillar surfaces in the common equipment used in health-care
and consumer industries.