Eucalmaidins A−E, (+)-Oleuropeic Acid Derivatives from the Fresh Leaves of Eucalyptus maideni
journal contributionposted on 25.09.2009, 00:00 by Li-Wen Tian, Ying-Jun Zhang, Yi-Fei Wang, Chi-Choi Lai, Chong-Ren Yang
Five new (+)-oleuropeic acid derivatives, eucalmaidins A−E (1−5), together with 12 known compounds (6−17), were isolated from the fresh leaves of Eucalyptus maideni. Structures of the new compounds were determined on the basis of spectroscopic analyses (HSQC, HMBC, and 1H−1H COSY), chemical degradation, and enzymatic hydrolysis. Of the tested compounds, only quercetin showed slight anti-herpes simplex virus 1 (HSV-1) activity in vitro.