American Chemical Society
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Enantioselective Synthesis of (−)-Pentalenene

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journal contribution
posted on 2007-12-20, 00:00 authored by Mahesh K. Pallerla, Joseph M. Fox
A short, enantioselective synthesis of (−)-pentalenene is described. Catalytic enantioselective cyclopropenation with (R,R)-Rh2(OAc)(DPTI)3 was used to set the absolute stereochemistry, and an intramolecular Pauson−Khand reaction of the resulting cyclopropenyne was used to establish the quaternary center.