American Chemical Society
ol5b03664_si_001.pdf (3.23 MB)

Enantioselective Synthesis of α‑Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation

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journal contribution
posted on 2016-02-01, 00:00 authored by Zhong Yan, Bo Wu, Xiang Gao, Mu-Wang Chen, Yong-Gui Zhou
A highly enantioselective palladium-catalyzed hydrogenation of a series of linear and cyclic α-iminophosphonates has been achieved, providing efficient access to optically active α-aminophosphonates with up to 99% ee.