ol0059596_si_001.pdf (1.06 MB)
Enantioselective Copper-Catalyzed Conjugate Addition of Dialkyl Zinc to Nitro-Olefins
journal contributionposted on 02.08.2000, 00:00 by Alexandre Alexakis, Cyril Benhaim
The copper-catalyzed asymmetric conjugate addition of dialkylzinc onto various nitro-olefins has been carried out with excellent results. An enantiomeric excess of up to 94% was obtained using 0.5% Cu(OTf)2 and 1% of chiral trivalent phosphorus ligand.