Electrosynthesis of Trisubstituted 2‑Oxazolines via Dehydrogenative Cyclization of β‑Amino Arylketones

An electrochemically intramolecular functionalization of C­(sp³)–H bonds with masked oxygen nucleophiles was developed. With KI as the catalyst and electrolyte, diverse trisubstituted 2-oxazolines were constructed in good to excellent yields. This newly developed electrochemical dehydrogenative approach features external oxidant-free and additive-free conditions.