ol301194e_si_001.pdf (1.53 MB)
Efficient Synthesis of α-Tertiary α-Silylamines from Aryl Sulfonylimidates via One-Pot, Sequential C–Si/C–C Bond Formations
journal contributionposted on 2012-06-01, 00:00 authored by Xiao-Jun Han, Ming Yao, Chong-Dao Lu
An efficient and flexible route for the synthesis of α-tertiary (α,α-dibranched) α-silylamines via sequential reactions of sulfonylimidates using readily available phenyldimethylsilyllithium and Grignard reagents is described. The procedure allows successive formation of C–Si/C–C bonds in a single flask.