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Effect of Interfacial Interaction on the Cross-Sectional Morphology of Tobacco Mosaic Virus Using GISAXS
journal contribution
posted on 2007-10-23, 00:00 authored by Byeongdu Lee, Chieh-Tsung Lo, P. Thiyagarajan, Randall E. Winans, Xuefa Li, Zhongwei Niu, Qian WangWe have investigated the effect of the interfacial interaction on the cross-sectional morphology of the tobacco
mosaic virus (TMV) in solution and on two types of solid substrates, SiOx (polar) on Si(100) and polystyrene film
(nonpolar) on Si(100), using small-angle X-ray scattering (SAXS) and grazing incidence small-angle X-ray scattering
(GISAXS), respectively. Results reveal that the flexible chains at the outer surface of TMV either expand or contract
depending on the nature of the substrate. Although the unfavorable interaction between the TMV and the PS causes
a minimal effect, the stronger attractive interaction between the outer protein surface of TMV and the SiOx substrate
induces pronounced deformation of its cross-sectional morphology.