posted on 2024-02-23, 15:35authored byYu Liu, Xiaoyi Yan, Yue Xing, Puyu Zhao, Yunxue Zhu, Luo Li, Ning Liu, Zhiquan Zhang
In this study, the gold nanoparticles (AuNPs) supported
by a covalent
organic framework (COF) were designed and produced by a self-reduction
method, which could effectively avoid the aggregation of AuNPs. The
amino and aldehyde groups in the COF are crucial for the self-reduction
of AuNPs. The porous COF with a high specific surface area not only
serves as an anchoring platform for AuNPs but also enhances the adsorption
abilities toward acetaminophen (AP). The AuNPs can facilitate the
electron transfer capabilities of the catalyst and enhance the electrocatalytic
activity of the catalyst. Due to the excellent electrical conductivity
of carbon nanotubes, COF@AuNPs were composited with multi-walled carbon
nanotubes (MWCNTs) by the ultrasound method. COF@AuNPs@MWCNTs were
applied to build an electrochemical sensing platform to measure AP.
The COF@AuNPs@MWCNTs/GCE displays a wide detection range for AP (0.1–500,
500–1200 μM) with a detection limit of 80 nM. The constructed
electrochemical sensor can be utilized for the assay of AP in the
actual sample serum with recoveries of 98.20–102.2%. Such a
self-reducing synthesis method opens up perspectives for the design
of COF@metal NPs for a broad range of applications such as sensing,
energy, and catalysis.