ol800092p_si_002.pdf (8.29 MB)
Download file

Direct Carbocyclization of Aldehydes with Alkynes:  Combining Gold Catalysis with Aminocatalysis

Download (8.29 MB)
journal contribution
posted on 06.03.2008, 00:00 by Jörg T. Binder, Benedikt Crone, Timm T. Haug, Helge Menz, Stefan F. Kirsch
A combination of gold(I) complexes and amine bases catalyzes the 5-exo-dig cyclization of formyl alkynes. This direct α-functionalization of aldehydes with unactivated alkynes does not involve the use of preformed enol equivalents.