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Direct Access to Anthranilic Acid Derivatives via CO2 Incorporation Reaction Using Arynes

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journal contribution
posted on 04.09.2008, 00:00 by Hiroto Yoshida, Takami Morishita, Joji Ohshita
CO2 was found to be directly convertible into anthranilic acid derivatives of great synthetic value through a three-component coupling using arynes and amines. Zwitterions arising from nucleophilic attack of amines to arynes serve as key intermediates in the coupling.

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