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Development of Upconversion Luminescent Probe for Ratiometric Sensing and Bioimaging of Hydrogen Sulfide

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journal contribution
posted on 23.07.2014, 00:00 by Shujuan Liu, Lili Zhang, Tianshe Yang, Huiran Yang, Kenneth Yin Zhang, Xin Zhao, Wen Lv, Qi Yu, Xinglin Zhang, Qiang Zhao, Xiangmei Liu, Wei Huang
Merocyanines adsorbed into the mesopores of mSiO2 shell of NaYF4: 20% Yb, 2% Er, 0.2% Tm nanocrystals are demonstrated as ratiometric upconversion luminescence (UCL) probe for highly selective detection of HS in living cells through inhibition of energy transfer from the UCL of the nanocrystals to the absorbance of the merocyanines. The UCL probe has been used for ratiometric sensing of H2S with high sensitivity and selectivity.

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