ol5b01554_si_001.pdf (4.36 MB)

Dehydrogenative [2 + 2 + 2] Cycloaddition of Cyano-yne-allene Substrates: Convenient Access to 2,6-Naphthyridine Scaffolds

Download (4.36 MB)
journal contribution
posted on 19.06.2015, 00:00 by Ewelina Haraburda, Agustí Lledó, Anna Roglans, Anna Pla-Quintana
A rhodium-catalyzed [2 + 2 + 2] cycloaddition of cyano-yne-allene scaffolds followed by a dehydrogenative process enabling the direct synthesis of unsaturated pyridine-containing compounds that can be conveniently converted to 2,6-naphthyridine derivatives is reported.