DNA-Based Networks Formed by Coordination Cross-Linking of DNA with Metal–Organic Polyhedra: From Gels to Aerogels to Hydrogels

Herein, we introduce a supramolecular method to form DNA-based networks by cross-linking DNA with Rh(II)-based metal–organic polyhedra (MOPs), which entails coordination of DNA to the exohedral Rh(II) axial sites of the MOP. The resultant highly connected networks can then be processed into gels, porous aerogels, or hydrogels, exhibiting properties suitable for pollutant removal and drug release.