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Cytotoxic Triterpenoids from the Rhizomes of Astilbe chinensis

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journal contribution
posted on 24.07.2009, 00:00 by Xing-Fu Cai, Bo-Young Park, Kyung-Seop Ahn, Ok-Kyoung Kwon, Hyeong-Kyu Lee, Sei-Ryang Oh
Six new triterpenoids (16) with a carboxylic acid functionality at C-27 were isolated from the rhizomes of a Korean native perennial herb, Astilbe chinensis, along with nine known triterpenoids. The structures of 16 were elucidated on the basis of spectroscopic data interpretation. All compounds isolated were evaluated for cytotoxic effects against a small panel of human cancer lines.