Cycloadditions
of Cyclohexynes and Cyclopentyne

Medina, Jose M.; McMahon, Travis
C.; Jiménez-Osés, Gonzalo; Houk, K. N.; Garg, Neil K.

doi:10.1021/ja508635v.s001

Cycloadditions of Cyclohexynes and Cyclopentyne

journal contribution

posted on 2015-12-17, 05:22 authored by Jose M. Medina, Travis C. McMahon, Gonzalo Jiménez-Osés, K. N. Houk, Neil K. Garg

We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described. The observed regioselectivities are explained by the distortion/interaction model.

History

Usage metrics

Keywords

distortion CyclopentyneWe report Cyclohexyne hetero synthesis tool regio cyclo compound Experimental model Cycloaddition

Licence

CC BY-NC 4.0

Cycloadditions of Cyclohexynes and Cyclopentyne

History

Usage metrics

Categories

Keywords

Licence

Exports