posted on 2019-11-26, 14:45authored byBojan Vulovic, Milena Trmcic, Radomir Matovic, Radomir N. Saicic
Unsaturated oxyallyl cations with a suitably positioned
alkene
bond undergo 5-exo-cyclization with the formation
of vinylcyclopentane derivatives. Alkyne analogues provide allenes.
The reaction proceeds with a moderate to excellent level of stereoselectivity
and allows for asymmetric induction in the reaction with chiral substrate.