ja0393729_si_001.pdf (580.71 kB)
Cross-Couplings of Alkyl Electrophiles under “Ligandless” Conditions: Negishi Reactions of Organozirconium Reagents
journal contributionposted on 2004-01-14, 00:00 authored by Sheryl L. Wiskur, Alexander Korte, Gregory C. Fu
This report establishes that simple, “ligandless” palladium complexes can catalyze the first zirconium-Negishi reactions of alkyl electrophiles. In view of the attractiveness of ligandless catalysts (cost, simplicity, and ease of purification), these observations add a significant and intriguing new dimension to the development of effective palladium-based processes for coupling alkyl electrophiles.