Copper-Mediated Reaction of Zirconacyclopentadienes
with Azides: A One-Pot Three-Component
Synthesis of Multiply Substituted Pyrroles from One Azide and Two
Alkynes
posted on 2013-11-11, 00:00authored byYiqing Zhou, Xiaoyu Yan, Chao Chen, Chanjuan Xi
A general
method for the synthesis of multiply substituted pyrroles
through zirconocene-mediated coupling of two alkynes and an azide
in the presence of CuCl has been achieved.