American Chemical Society
jo8b02821_si_002.pdf (4.68 MB)

Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles

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journal contribution
posted on 2019-01-20, 00:00 authored by Lukasz Przypis, Krzysztof Zdzislaw Walczak
A copper-catalyzed iodination of carbazoles has been developed. Barluenga’s reagent IPy2BF4 is used to generate a soft electrophilic halonium species for the iodination of the carbazoles. This report represents the first concept of copper-catalyst-promoted electrophilic halogenation of carbazoles. We demonstrated numerous applications of this methodology synthesizing diverse carbazole derivatives, i.e., both electron-rich and electron-deficient systems.