jo8b02821_si_002.pdf (4.68 MB)
Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles
journal contribution
posted on 2019-01-20, 00:00 authored by Lukasz Przypis, Krzysztof Zdzislaw WalczakA copper-catalyzed
iodination of carbazoles has been developed.
Barluenga’s reagent IPy2BF4 is used to generate a soft electrophilic
halonium species for the iodination of the carbazoles. This report
represents the first concept of copper-catalyst-promoted electrophilic
halogenation of carbazoles. We demonstrated numerous applications
of this methodology synthesizing diverse carbazole derivatives, i.e.,
both electron-rich and electron-deficient systems.