jo902160y_si_001.pdf (813.81 kB)
0/0

Copper-Catalyzed Synthesis of 2-Unsubstituted, N-Substituted Benzimidazoles

Download (813.81 kB)
journal contribution
posted on 18.12.2009 by Keiichi Hirano, Akkattu T. Biju, Frank Glorius
An efficient copper-catalyzed intramolecular arylation of formamidines forming 2-unsubstituted benzimidazoles in excellent yields is reported. Sixteen examples bearing sterically demanding substituents on nitrogen like Mes, 2,6-diisopropylphenyl, or 2-tert-butylphenyl and tolerating various functional groups demonstrate the utility of this method.

History

Exports