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Copper-Catalyzed Oxyazidation of Unactivated Alkenes: A Facile Synthesis of Isoxazolines Featuring an Azido Substituent

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journal contribution
posted on 21.03.2014, 00:00 by Liping Zhu, Hongmei Yu, Zhaoqing Xu, Xianxing Jiang, Li Lin, Rui Wang
A novel and efficient Cu­(OAc)2-catalyzed oxyazidation of unactivated alkenes was developed. The reactions are easy to conduct, occur under mild conditions, and form azido-substituted isoxazolines in good yields.