Copper Acetate–DMSO
Promoted Methylthiolation
of Arenes and Heteroarenes

Sharma, Poonam; Rohilla, Sandeep; Jain, Nidhi

doi:10.1021/acs.joc.5b00443.s001

jo5b00443_si_001.pdf (2.76 MB)

Copper Acetate–DMSO Promoted Methylthiolation of Arenes and Heteroarenes

journal contribution

posted on 2015-04-17, 00:00 authored by Poonam Sharma, Sandeep Rohilla, Nidhi Jain

An unprecedented copper acetate–DMSO promoted methylthiolation of arenes and heteroarenes in the presence of air has been developed. The reaction is highly regioselective under the directing group influence of pyridine and pyrimidine functional units and gives the thiomethylated product in moderate to high yields.