Cooperative Hydrogen-Bonding Effects in Silanediol Catalysis
journal contributionposted on 06.01.2012, 00:00 by Ngon T. Tran, Sean O. Wilson, Annaliese K. Franz
The importance of cooperative hydrogen-bonding effects and SiOH-acidification is described for silanediol catalysis. NMR binding, X-ray, and computational studies provide support for a unique dimer resulting from silanediol self-recognition. The significance of this cooperative hydrogen-bonding is demonstrated using novel fluorinated silanediol catalysts for the addition of indoles and N,N-dimethyl-m-anisidine to trans-β-nitrostyrene.