Concise Total Synthesis of (±)-Aloperine and 6-epi-Aloperine
journal contributionposted on 27.07.2002, 00:00 by Daniele Passarella, Marco Angoli, Alessandra Giardini, Giordano Lesma, Alessandra Silvani, Bruno Danieli
Total synthesis of aloperine and 6-epi-aloperine is reported. The crucial steps of the synthetic strategy are an aza-annulation reaction and an intermolecular Diels−Alder reaction. The synthetic plan proceeds from commercially available piperidine-2-ethanol.