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Concise Total Synthesis and Stereochemical Revision of all (−)-Trigonoliimines

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journal contribution
posted on 20.07.2011, 00:00 by Sunkyu Han, Mohammad Movassaghi
The concise and enantioselective total syntheses of (−)-trigonoliimines A, B, and C are described. Our unified strategy to all three natural products is based on asymmetric oxidation and reorganization of a single bistryptamine, a sequence of transformations with possible biogenetic relevance. We revise the absolute stereochemistry of (−)-trigonoliimines A, B, and C.