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Cobalt-Catalyzed Oxidative Annulation of Benzothiophene‑[b]‑1,1-dioxide through Diastereoselective Double C–H Activation

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journal contribution
posted on 25.10.2019, 12:04 by Subban Kathiravan, Ian A. Nicholls
The use of inexpensive base metal catalysis to perform C–H activation is an active field of research in organic synthesis. Described herein is a sustainable cobalt-catalyzed diastereoselective oxidative annulation/double C–H activation of benzothiophene-[b]-1,1-dioxide with aminoquinolinamides under mild reaction conditions for the synthesis of annulated benzothiophenes.

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