om700822a_si_001.pdf (162.52 kB)
Catalytic Carbon−Hydrogen Bond Functionalization in an Ionic Liquid Medium
journal contributionposted on 2007-12-17, 00:00 authored by Pilar Rodríguez, Eleuterio Álvarez, M. Carmen Nicasio, Pedro J. Pérez
The functionalization of unreactive C−H bonds of several hydrocarbons has been achieved at room temperature by the formal insertion of carbene/CHCO2Et units (from ethyl diazoacetate) into such bonds, using copper-based catalysts in a biphasic reaction medium (ionic liquid-hydrocarbon). Catalyst and product separation has been carried out easily, and the recycle of the catalyst for five cycles has been achieved without any loss of catalytic activity.