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Caminoside A, an Antimicrobial Glycolipid Isolated from the Marine Sponge Caminus sphaeroconia

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journal contribution
posted on 16.10.2002, 00:00 by Roger G. Linington, Marilyn Robertson, Annick Gauthier, B. Brett Finlay, Rob van Soest, Raymond J. Andersen
Extracts of the marine sponge Caminus sphaeroconia showed potent activity in a screen for bacterial type III secretion inhibitors. Bioassay guided fractionation of the extract led to the isolation of the novel antimicrobial glycolipid caminoside A (1). The structure of caminoside A was elucidated by analysis of spectroscopic data and chemical degradation.