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Brønsted Acid-Mediated Nazarov Cyclization of Vinylallenes

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journal contribution
posted on 06.08.2010, 00:00 by Yen-Ku Wu, F. G. West
Treatment of siloxy enynes with base leads to the corresponding vinylsiloxyallenes which undergo Nazarov cyclization in the presence of trifluoroacetic acid to provide the cyclized product as a mixture of regioisomers in moderate to good overall yield.