American Chemical Society
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Boron Trifluoride Mediated Ring-Opening Reactions of trans-2-Aryl-3-nitro-cyclopropane-1,1-dicarboxylates. Synthesis of Aroylmethylidene Malonates as Potential Building Blocks for Heterocycles

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journal contribution
posted on 2014-04-18, 00:00 authored by Thangavel Selvi, Kannupal Srinivasan
trans-2-Aryl-3-nitro-cyclopropane-1,1-dicarboxylates, upon treatment with BF3·​OEt2, undergo ring-opening rearrangement and the Nef reaction to give aroylmethylidene malonates. The products are found to be potential precursors for heterocycles, such as imidazoles, quinoxalines, and benzo­[1,4]­thiazines.