posted on 2016-02-20, 19:26authored byThanh Binh Nguyen, Jonathan Sorres, Minh Quan Tran, Ludmila Ermolenko, Ali Al-Mourabit
A novel method of transamidation of carboxamides with amines using catalytic amounts of readily available boric acid under solvent-free conditions has been developed. The scope of the methodology has been demonstrated with (i) primary, secondary, and tertiary amides and phthalimide and (ii) aliphatic, aromatic, cyclic, acyclic, primary, and secondary amines.