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Bisnorditerpene, Norditerpene, and Lipo-alkaloids from Aconitum toxicum

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journal contribution
posted on 24.10.2008, 00:00 by Dezső Csupor, Peter Forgo, Eva Maria Wenzig, Rudolf Bauer, Judit Hohmann
From the roots of Aconitum toxicum, acotoxicine (1), a new bisnorditerpene alkaloid, was isolated together with the structurally related delavaconitine, delavaconine, dolaconine, aconosine, and the norditerpene alkaloid neolinine. The structure of compound 1 was elucidated by spectroscopic data interpretation. Further, eight lipo-alkaloids (29) were detected in the plant material by LC-APCI-MSn analysis. This is the first report of a C18 bisnorditerpene alkaloid and lipo-alkaloids from A. toxicum.