posted on 2023-12-21, 21:04authored bySangik Lee, Jaehee Sim, Anna Lee
We developed a novel and efficient
sequential one-pot synthesis
of selenosulfides via a base-catalyzed methodology utilizing readily
available starting compounds, under mild reaction conditions. This
method eliminated the need for excess oxidants or additives and simplified
the synthesis procedure. Furthermore, organic amine bases served as
exceptional catalysts for synthesizing the target products. The performance
of a catalytic system depends on the basicity of the bases. The selection
of suitable bases, based on their pKaH values, is crucial for the selective synthesis of selenosulfides
without the formation of byproducts. This method provides a direct
route for the preparation of selenosulfides, which are important scaffolds
in organic chemistry.