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Download fileB(C6F5)3‑Catalyzed Michael Reactions: Aromatic C–H as Nucleophiles
journal contribution
posted on 11.05.2017, 00:00 authored by Wu Li, Thomas WernerThe Michael reaction
is a widely used reaction for the C–C
coupling of electron-poor olefins and C(sp3)–H pronucleophiles.
Herein we report the Michael reaction between alkenes and aromatic
as well as heteroaromatic compounds as aromatic C(sp2)–H
nucleophiles under mild conditions. The reaction is catalyzed by readily
available Lewis acidic B(C6F5)3 and
proceeds with high regioselectivity for a wide substrate scope.