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B(C6F5)3‑Catalyzed Michael Reactions: Aromatic C–H as Nucleophiles

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journal contribution
posted on 11.05.2017, 00:00 by Wu Li, Thomas Werner
The Michael reaction is a widely used reaction for the C–C coupling of electron-poor olefins and C­(sp3)–H pronucleophiles. Herein we report the Michael reaction between alkenes and aromatic as well as heteroaromatic compounds as aromatic C­(sp2)–H nucleophiles under mild conditions. The reaction is catalyzed by readily available Lewis acidic B­(C6F5)3 and proceeds with high regioselectivity for a wide substrate scope.

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