ol7b00720_si_001.pdf (919.51 kB)
Download file

B(C6F5)3‑Catalyzed Michael Reactions: Aromatic C–H as Nucleophiles

Download (919.51 kB)
journal contribution
posted on 11.05.2017, 00:00 authored by Wu Li, Thomas Werner
The Michael reaction is a widely used reaction for the C–C coupling of electron-poor olefins and C­(sp3)–H pronucleophiles. Herein we report the Michael reaction between alkenes and aromatic as well as heteroaromatic compounds as aromatic C­(sp2)–H nucleophiles under mild conditions. The reaction is catalyzed by readily available Lewis acidic B­(C6F5)3 and proceeds with high regioselectivity for a wide substrate scope.