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Azoles as Suzuki Cross-Coupling Leaving Groups:  Syntheses of 6-Arylpurine 2‘-Deoxynucleosides and Nucleosides from 6-(Imidazol-1-yl)- and 6-(1,2,4-Triazol-4-yl)purine Derivatives1

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journal contribution
posted on 16.09.2004, 00:00 by Jiangqiong Liu, Morris J. Robins
6-(Imidazol-1-yl)-, 6-(benzimidazol-1-yl)-, and 6-(1,2,4-triazol-4-yl)purine nucleosides undergo a nickel-mediated C−C cross-coupling of azole-substituted purine derivatives with arylboronic acids to give good yields of 6-arylpurine nucleosides.

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