Atom Economical, One-Pot, Three-Reaction Cascade to Novel Tricyclic 2,4-Dihydro‑1H‑benzo[f]isochromenes

Reaction of 6-methyl-1-phenylhept-3-yne-2,6-diol with various aldehydes under Lewis acid conditions provides an atom economical, two-component cascade reaction sequence to novel 2,4-dihydro-1H-benzo[f]isochromene compounds. Aliphatic aldehydes as well as electron-deficient and -rich aromatic aldehydes can be used.