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Artocarmins G–M, Prenylated 4‑Chromenones from the Stems of Artocarpus rigida and Their Tyrosinase Inhibitory Activities

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journal contribution
posted on 11.12.2017, 21:06 by Mai T. T. Nguyen, Tho H. Le, Hai X. Nguyen, Phu H. Dang, Truong N. V. Do, Manabu Abe, Ryukichi Takagi, Nhan T. Nguyen
Phytochemical analysis of an EtOAc extract of the stems of Artocarpus rigida led to the identification of seven new prenylated 4-chromenones, artocarmins G–M (17), and nine known compounds (817). Their structures were identified based on physical data analysis. In the tyrosinase inhibitory activity test, norartocarpetin (8) displayed the strongest effect, with an IC50 value of 0.023 μM.