An
efficient anodic C(sp3)–H acyloxylation protocol
has been established via intermolecular cross-dehydrogenative C(sp3)–O coupling. The protocol provides various C2-acyloxy
indolin-3-ones without the addition of metal catalysts and external
oxidants because indolin-3-ones can be directly oxidized at the anode.
The effective application of several medical drugs and the realization
of the gram-scale experiment have proven the practicality of this
protocol.