ol049633z_si_001.pdf (166.66 kB)

An Unusual Approach to the Synthesis of Enantiomerically Cis Linear Homoallylic Alcohols Based on the Steric Interaction Mechanism of Camphor Scaffold

Download (166.66 kB)
journal contribution
posted on 15.04.2004, 00:00 by Chi-Lik Ken Lee, Cheng-Hsia Angeline Lee, Kui-Thong Tan, Teck-Peng Loh
Camphor is used as the chiral auxiliary for the enantioselective synthesis of cis linear homoallylic alcohols. A range of catalysts, aldehydes, and solvents were investigated to obtain the optimum yield, enantioselectivity, and cis olefinic geometry.