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An Electroneutral Macrocyclic Iron(II) Complex That Enhances MRI Contrast in Vivo

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journal contribution
posted on 23.06.2011, 00:00 by Fayçal Touti, Akhilesh Kumar Singh, Philippe Maurin, Laurence Canaple, Olivier Beuf, Jacques Samarut, Jens Hasserodt
The first example of a macrocyclic ferrous complex, where two tetrazolyl pendent arms compensate the charge of the metal center, is synthesized and examined for its capacity to enhance MRI contrast in vitro and in vivo in the mouse.