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Amphidinolides B6 and B7, Cytotoxic Macrolides from a Symbiotic Dinoflagellate Amphidinium Species

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posted on 2007-10-26, 00:00 authored by Keiko Oguchi, Masashi Tsuda, Rie Iwamoto, Yumiko Okamoto, Taeko Endo, Jun’ichi Kobayashi, Tomoko Ozawa, Atsunori Masuda
Two 26-membered macrolides, amphidinolides B6 (2) and B7 (1), have been isolated from a marine symbiotic dinoflagellate Amphidinium sp., and the structures were elucidated on the basis of detailed analyses of 2D NMR data. The relative and absolute configurations for 1 and 2 were assigned by comparison of NMR data and CD data with those of known amphidinolides.

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