American Chemical Society
jo0487911_si_001.pdf (6.69 MB)

Alkynyliodonium Salts in Organic Synthesis. Application to the Preparation of the Tricyclic Core of (±)-Halichlorine

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journal contribution
posted on 2004-11-12, 00:00 authored by Ken S. Feldman, Angela L. Perkins, Katherine M. Masters
The tricyclic core of halichlorine has been synthesized through the use of an alkynyliodonium salt/alkylidenecarbene/1,5 C−H insertion sequence that sets the pivotal quaternary center in the target.