Alkyne [2 + 2 + 2] Cyclotrimerization Catalyzed by
a Low-Valent Titanium Reagent Derived from CpTiX3 (X =
Cl, O‑i‑Pr), Me3SiCl, and
Mg or Zn

Okamoto, Sentaro; Yamada, Takeshi; Tanabe, Yu-ki; Sakai, Masaki

doi:10.1021/acs.organomet.8b00678.s001

om8b00678_si_001.pdf (36.89 MB)

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Alkyne [2 + 2 + 2] Cyclotrimerization Catalyzed by a Low-Valent Titanium Reagent Derived from CpTiX₃ (X = Cl, O‑i‑Pr), Me₃SiCl, and Mg or Zn

journal contribution

posted on 2018-10-29, 19:37 authored by Sentaro Okamoto, Takeshi Yamada, Yu-ki Tanabe, Masaki Sakai

Inter-, partially intra-, and intramolecular [2 + 2 + 2] cycloadditions of alkynes were catalyzed by a low-valent titanium species generated in situ from the reduction of CpTi(O-i-Pr)₃, CpTiCl₃, or Cp*TiCl₃ with Mg or Zn powder in the presence of Me₃SiCl. The role of Me₃SiCl as an additive in the reaction mechanism is discussed.