Air-Stable Secondary Phosphine Oxide or Chloride (Pre)Ligands for Cross-Couplings of Unactivated Alkyl Chlorides

In situ generated and crystallographically well-defined, isolated palladium complexes derived from seven novel air-stable secondary phosphine oxides or chlorides enabled challenging Kumada−Corriu cross-couplings of unactivated alkyl chlorides bearing β-hydrogens and proved applicable to transformations of alkyl-substituted organometallics.