AgNO<sub>2</sub> as the NO Source for the Synthesis of Substituted Pyrazole <i>N</i>‑Oxides from <i>N</i>‑Propargylamines
journal contribution
posted on 2016-11-01, 19:51 authored by Bingxiang Yuan, Fuming Zhang, Zhuomei Li, Shenghua Yang, Rulong YanA straightforward
method
for synthesizing the pyrazole <i>N</i>-oxides from <i>N</i>-propargylamines and AgNO<sub>2</sub> through oxidation/cyclization
reaction had been developed. AgNO<sub>2</sub> was used as the NO source
for the first time to synthesize pyrazole <i>N</i>-oxides.
Various substituted groups on <i>N</i>-propargylamines proceeded
smoothly, and the desired products were obtained in good yields.
