Acyclic Cucurbit[n]uril Dendrimers

The synthesis of acyclic cucurbit­[n]­uril dendrimers G1–G3 that bear four dendrons on their aromatic sidewalls via thiolate S_N2 chemistry is reported. G1–G3 are polycationic and can bind to pEGFP plasmid DNA as shown by dynamic light scattering (DLS), gel electrophoresis, and scanning electron microscopy (SEM). The gene delivery ability of G1–G3 is presented.