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Acremostrictin, a Highly Oxygenated Metabolite from the Marine Fungus Acremonium strictum

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posted on 2011-12-27, 00:00 authored by Elin Julianti, Hana Oh, Kyoung Hwa Jang, Jae Kyun Lee, Sang Kook Lee, Dong-Chan Oh, Ki-Bong Oh, Jongheon Shin
The novel natural product acremostrictin (1) was isolated from the culture broth of Acremonium strictum, a marine fungus collected from a Choristida sponge off the coast of Korea. Structurally, acremostrictin is a tricyclic lactone of an unprecedented skeletal class based on combined spectroscopic and X-ray crystallographic analyses. The new compound exhibited weak antibacterial and moderate antioxidant activities.

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