np200707y_si_001.pdf (864.79 kB)
Acremostrictin, a Highly Oxygenated Metabolite from the Marine Fungus Acremonium strictum
journal contribution
posted on 2011-12-27, 00:00 authored by Elin Julianti, Hana Oh, Kyoung Hwa Jang, Jae Kyun Lee, Sang Kook Lee, Dong-Chan Oh, Ki-Bong Oh, Jongheon ShinThe novel natural product acremostrictin (1) was isolated
from the culture broth of Acremonium strictum, a
marine fungus collected from a Choristida sponge off the coast of
Korea. Structurally, acremostrictin is a tricyclic lactone of an unprecedented
skeletal class based on combined spectroscopic and X-ray crystallographic
analyses. The new compound exhibited weak antibacterial and moderate
antioxidant activities.